NAGLU antibody (AA 24-489) (Biotin)

Catalog No. ABIN8012985

The Rabbit Polyclonal anti-NAGLU antibody is suitable to detect NAGLU in samples from Mouse, Human and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for NAGLU antibody (AA 24-489) (Biotin) (ABIN8012985)

Target: NAGLU (N-Acetylglucosaminidase, alpha (NAGLU))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAGLU antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-NAGLU Antibody (Biotin)

Binding Specificity: AA 24-489

Purpose: Anti-NAGLU Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NAGLU recombinant protein (Position: D24-D489).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NAGLU

Target: NAGLU (N-Acetylglucosaminidase, alpha (NAGLU))

Alternative Name: NAGLU

Background:

Background: N-acetylglucosaminidase, alpha is a protein that in humans is encoded by the NAGLU gene. This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate.

Gene Full Name: N-acetyl-alpha-glucosaminidase

Gene ID: 4669

UniProt: P54802

Pathways: Glycosaminoglycan Metabolic Process