NAGLU antibody (AA 24-489) (Fluoro488)

Catalog No. ABIN8012987

This Rabbit Polyclonal antibody specifically detects NAGLU in FACS. It exhibits reactivity toward Mouse, Human and Rat.

Quick Overview for NAGLU antibody (AA 24-489) (Fluoro488) (ABIN8012987)

Target: NAGLU (N-Acetylglucosaminidase, alpha (NAGLU))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAGLU antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-NAGLU Antibody (Fluoro488)

Binding Specificity: AA 24-489

Purpose: Anti-NAGLU Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NAGLU recombinant protein (Position: D24-D489).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NAGLU

Target: NAGLU (N-Acetylglucosaminidase, alpha (NAGLU))

Alternative Name: NAGLU

Background:

Background: N-acetylglucosaminidase, alpha is a protein that in humans is encoded by the NAGLU gene. This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate.

Gene Full Name: N-acetyl-alpha-glucosaminidase

Gene ID: 4669

UniProt: P54802

Pathways: Glycosaminoglycan Metabolic Process