NMI antibody (AA 2-307) (Cy3)

Catalog No. ABIN8013196

The Cy3-conjugated Mouse Monoclonal anti-NMI antibody (Clone 2F3) (ABIN8013196) specifically detects NMI in FACS. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for NMI antibody (AA 2-307) (Cy3) (ABIN8013196)

Target: NMI (N-Myc (And STAT) Interactor (NMI))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This NMI antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Clone: 2F3

Product Details anti-NMI Antibody (Cy3)

Binding Specificity: AA 2-307

Purpose: Anti-NMI Antibody (monoclonal, 2F3) Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: Human NMI shares 64% amino acid (aa) sequence identity with mouse NMI.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NMI recombinant protein (Position: E2-E307). Human NMI shares 64% amino acid (aa) sequence identity with mouse NMI.

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NMI

Target: NMI (N-Myc (And STAT) Interactor (NMI))

Alternative Name: NMI

Background:

Background: NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.

Gene Full Name: N-myc and STAT interactor

Gene ID: 9111

UniProt: Q13287