SGSH antibody (AA 206-502) (Fluoro550)

Catalog No. ABIN8013231

The Rabbit Polyclonal anti-SGSH antibody is suitable to detect SGSH in samples from Human, Rat and Mouse. It has been validated for FACS.

Quick Overview for SGSH antibody (AA 206-502) (Fluoro550) (ABIN8013231)

Target: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGSH antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-SGSH Antibody (Fluoro550)

Binding Specificity: AA 206-502

Purpose: Anti-HSS/SGSH Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HSS/SGSH recombinant protein (Position: R206-L502).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SGSH

Target: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Alternative Name: SGSH

Background:

Background: N-sulphoglucosamine sulphohydrolase is an enzyme that in humans is encoded by the SGSH gene. This gene encodes the enzyme sulfamidase, one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with the lysosomal storage disease mucopolysaccaridosis IIIA, also known as Sanfilippo syndrome A, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined.

Gene Full Name: N-sulfoglucosamine sulfohydrolase

Gene ID: 6448

UniProt: P51688

Pathways: Glycosaminoglycan Metabolic Process