NECAB3 antibody (AA 97-339) (Fluoro488)

Catalog No. ABIN8013263

This Rabbit Polyclonal antibody specifically detects NECAB3 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NECAB3 antibody (AA 97-339) (Fluoro488) (ABIN8013263)

Target: NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NECAB3 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-NECAB3 Antibody (Fluoro488)

Binding Specificity: AA 97-339

Purpose: Anti-NECAB3 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NECAB3 recombinant protein (Position: D97-D339).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NECAB3

Target: NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

Alternative Name: NECAB3

Background:

Background: N-terminal EF-hand calcium-binding protein 3 is a protein that in humans is encoded by the NECAB3 gene. The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: N-terminal EF-hand calcium binding protein 3

Gene ID: 63941

UniProt: Q96P71