NCR1 antibody (AA 22-258) (Fluoro647)

Catalog No. ABIN8013930

The Rabbit Polyclonal anti-NCR1 antibody is suitable to detect NCR1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for NCR1 antibody (AA 22-258) (Fluoro647) (ABIN8013930)

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCR1 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-NCR1 Antibody (Fluoro647)

Binding Specificity: AA 22-258

Purpose: Anti-NCR1 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human NCR1 recombinant protein (Position: Q22-R258).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NCR1

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Alternative Name: NCR1

Background:

Background: Natural cytotoxicity triggering receptor 1, also known as NKp46, is a protein that in humans is encoded by the NCR1 gene. This gene is mapped to chromosome 19, where genes encoding other NK inhibitory and activator structures are also located. NKP46 participates in NK-cell-mediated lysis of cells infected with an intracellular bacterium and that reduced functional capacity of NK cells is associated with severe manifestations of infectious disease.

Gene Full Name: natural cytotoxicity triggering receptor 1

Gene ID: 9437

UniProt: O76036

Pathways: Regulation of Leukocyte Mediated Immunity