NDE1 antibody (AA 74-335) (APC)

Catalog No. ABIN8014038

The Rabbit Polyclonal anti-NDE1 antibody is suitable to detect NDE1 in samples from Human. It has been validated for FACS.

Quick Overview for NDE1 antibody (AA 74-335) (APC) (ABIN8014038)

Target: NDE1

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDE1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-NDE1 Antibody (APC)

Binding Specificity: AA 74-335

Purpose: Anti-NDE1 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NDE1 recombinant protein (Position: E74-C335).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NDE1

Target: NDE1

Alternative Name: NDE1

Background:

Background: Nuclear distribution protein nudE homolog 1 is a protein that in humans is encoded by the NDE1 gene. This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe cognitive disability. Alternative splicing results in multiple transcript variants.

Gene Full Name: nudE neurodevelopment protein 1

Gene ID: 54820

UniProt: Q9NXR1