NOVA1 antibody (AA 413-506) (APC)

Catalog No. ABIN8014621

The APC-conjugated Rabbit Polyclonal anti-NOVA1 antibody (ABIN8014621) specifically detects NOVA1 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NOVA1 antibody (AA 413-506) (APC) (ABIN8014621)

Target: NOVA1 (Neuro-Oncological Ventral Antigen 1 (NOVA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOVA1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-NOVA1 Antibody (APC)

Binding Specificity: AA 413-506

Purpose: Anti-Nova1 Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Nova1 recombinant protein (Position: T413-V506).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NOVA1

Target: NOVA1 (Neuro-Oncological Ventral Antigen 1 (NOVA1))

Alternative Name: NOVA1

Background:

Background: RNA-binding protein Nova-1 is a protein that in humans is encoded by the NOVA1 gene. It is mapped to 14q12. This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.

Gene Full Name: NOVA alternative splicing regulator 1

Gene ID: 4857

UniProt: P51513