NGEF antibody (AA 82-627) (Fluoro647)

Catalog No. ABIN8014920

The Rabbit Polyclonal anti-NGEF antibody is suitable to detect NGEF in samples from Human. It has been validated for FACS.

Quick Overview for NGEF antibody (AA 82-627) (Fluoro647) (ABIN8014920)

Target: NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NGEF antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-NGEF Antibody (Fluoro647)

Binding Specificity: AA 82-627

Purpose: Anti-NGEF Antibody Fluoro647 Conjugated

Predicted Reactivity: Human NGEF shares 91.1%,90.9% amino acid (aa) sequence identity with mouse,rat NGEF,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NGEF recombinant protein (Position: E82-Q627). Human NGEF shares 91.1% and 90.9% amino acid (aa) sequence identity with mouse and rat NGEF, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NGEF

Target: NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))

Alternative Name: NGEF

Background:

Background: Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including activation of GTPase activity, ephrin receptor signaling pathway, and negative regulation of dendritic spine morphogenesis. Predicted to be located in cytosol. Predicted to be active in glutamatergic synapse.

Gene Full Name: neuronal guanine nucleotide exchange factor

Gene ID: 25791

UniProt: Q8N5V2

Pathways: Neurotrophin Signaling Pathway