NGEF antibody (AA 82-627)

Catalog No. ABIN8014921

The Rabbit Polyclonal anti-NGEF antibody (ABIN8014921) specifically detects NGEF in WB, ELISA and FACS. The antibody is reactive with Human samples.

Quick Overview for NGEF antibody (AA 82-627) (ABIN8014921)

Target: NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NGEF antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-NGEF Antibody

Binding Specificity: AA 82-627

Purpose: Anti-NGEF Antibody

Predicted Reactivity: Human NGEF shares 91.1%,90.9% amino acid (aa) sequence identity with mouse,rat NGEF,respectively.

Characteristics: Anti-NGEF Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NGEF recombinant protein (Position: E82-Q627). Human NGEF shares 91.1% and 90.9% amino acid (aa) sequence identity with mouse and rat NGEF, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg /1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NGEF

Target: NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))

Alternative Name: NGEF

Background:

Background: Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including activation of GTPase activity, ephrin receptor signaling pathway, and negative regulation of dendritic spine morphogenesis. Predicted to be located in cytosol. Predicted to be active in glutamatergic synapse.

Gene Full Name: neuronal guanine nucleotide exchange factor

Molecular Weight: 71 kDa

Gene ID: 25791

UniProt: Q8N5V2

Pathways: Neurotrophin Signaling Pathway