NPTX2 antibody (AA 16-431) (Fluoro647)

Catalog No. ABIN8014942

The Fluoro647-conjugated Rabbit Polyclonal anti-NPTX2 antibody (ABIN8014942) specifically detects NPTX2 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NPTX2 antibody (AA 16-431) (Fluoro647) (ABIN8014942)

Target: NPTX2 (Neuronal Pentraxin II (NPTX2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPTX2 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-NPTX2 Antibody (Fluoro647)

Binding Specificity: AA 16-431

Purpose: Anti-NPTX2 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human NPTX2 shares 96.9%,95.7% amino acid (aa) sequence identity with mouse,rat NPTX2,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NPTX2 recombinant protein (Position: G16-L431). Human NPTX2 shares 96.9% and 95.7% amino acid (aa) sequence identity with mouse and rat NPTX2, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NPTX2

Target: NPTX2 (Neuronal Pentraxin II (NPTX2))

Alternative Name: NPTX2

Background:

Background: Neuronal pentraxin-2 is a protein that in humans is encoded by the NPTX2 gene. This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.

Gene Full Name: neuronal pentraxin 2

Gene ID: 4885

UniProt: P47972