NETO1 antibody (AA 5-514) (Biotin)

Catalog No. ABIN8015043

The Rabbit Polyclonal anti-NETO1 antibody is suitable to detect NETO1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for NETO1 antibody (AA 5-514) (Biotin) (ABIN8015043)

Target: NETO1 (Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NETO1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NETO1 Antibody (Biotin)

Binding Specificity: AA 5-514

Purpose: Anti-NETO1 Antibody Biotin Conjugated

Predicted Reactivity: Human NETO1 shares 95.7% amino acid (aa) sequence identity with mouse NETO1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NETO1 recombinant protein (Position: R5-R514). Human NETO1 shares 95.7% amino acid (aa) sequence identity with mouse NETO1.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NETO1

Target: NETO1 (Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1))

Alternative Name: NETO1

Background:

Background: Neuropilin (NRP) and tolloid (TLL)-like 1 is a protein that in humans is encoded by the NETO1 gene. This gene encodes a transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. This protein is thought to play a critical role in spatial learning and memory by regulating the function of synaptic N-methyl-D-aspartic acid receptor complexes in the hippocampus. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: neuropilin and tolloid like 1

Gene ID: 81832

UniProt: Q8TDF5

Pathways: Regulation of long-term Neuronal Synaptic Plasticity