Neurotrophin 3 antibody (C-Term) (Fluoro488)

Catalog No. ABIN8015210

This Rabbit Polyclonal antibody specifically detects Neurotrophin 3 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Neurotrophin 3 antibody (C-Term) (Fluoro488) (ABIN8015210)

Target: Neurotrophin 3 (NTF3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurotrophin 3 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Neurotrophin 3 Antibody (Fluoro488)

Binding Specificity: C-Term

Purpose: Anti-Neurotrophin 3/NTF3 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Neurotrophin 3/NTF3, which shares 89.3% and 95.3% amino acid (aa) sequence identity with mouse and rat Neurotrophin 3/NTF3, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Neurotrophin 3

Target: Neurotrophin 3 (NTF3)

Alternative Name: NTF3

Background:

Background: The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.

Gene Full Name: neurotrophin 3

Gene ID: 4908

UniProt: P20783

Pathways: RTK Signaling, Neurotrophin Signaling Pathway