Neurotrophin 4 antibody (Middle Region) (FITC)

Catalog No. ABIN8015235

The Rabbit Polyclonal anti-Neurotrophin 4 antibody is suitable to detect Neurotrophin 4 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for Neurotrophin 4 antibody (Middle Region) (FITC) (ABIN8015235)

Target: Neurotrophin 4 (NTF4)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurotrophin 4 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-Neurotrophin 4 Antibody (FITC)

Binding Specificity: Middle Region

Purpose: Anti-NT-4/NTF4 Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human NT-4/NTF4, which shares 83.3% amino acid (aa) sequence identity with both mouse and rat NT-4/NTF4.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Neurotrophin 4

Target: Neurotrophin 4 (NTF4)

Alternative Name: NTF4

Background:

Background: Neurotrophin-4 (NT-4), also known as neurotrophin-5 (NT-5), is a protein that in humans is encoded by the NTF4 gene. This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.

Gene Full Name: neurotrophin 4

Gene ID: 4909

UniProt: P34130

Pathways: RTK Signaling