NCF1 antibody (AA 22-384) (Fluoro488)

Catalog No. ABIN8015276

This Rabbit Polyclonal antibody specifically detects NCF1 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NCF1 antibody (AA 22-384) (Fluoro488) (ABIN8015276)

Target: NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCF1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-NCF1 Antibody (Fluoro488)

Binding Specificity: AA 22-384

Purpose: Anti-p47 phox/NCF1 Antibody Fluoro488 Conjugated

Predicted Reactivity: Human NCF1 shares 81% amino acid (aa) sequence identity with both mouse,rat NCF1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human p47 phox/NCF1 recombinant protein (Position: Q22-R384). Human NCF1 shares 81% amino acid (aa) sequence identity with both mouse and rat NCF1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NCF1

Target: NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

Alternative Name: NCF1

Background:

Background: Neutrophil cytosol factor 1, also known as p47phox, is a protein that in humans is encoded by the NCF1 gene. The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.

Gene Full Name: neutrophil cytosolic factor 1

Gene ID: 653361

UniProt: P14598

Pathways: PI3K-Akt Signaling