NFU1 antibody (AA 42-254) (FITC)

Catalog No. ABIN8015334

The Rabbit Polyclonal anti-NFU1 antibody is suitable to detect NFU1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for NFU1 antibody (AA 42-254) (FITC) (ABIN8015334)

Target: NFU1 (NFU1 Iron-Sulfur Cluster Scaffold (NFU1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFU1 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-NFU1 Antibody (FITC)

Binding Specificity: AA 42-254

Purpose: Anti-NFU1 Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human NFU1 shares 93% amino acid (aa) sequence identity with mouse NFU1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NFU1 recombinant protein (Position: Q42-P254). Human NFU1 shares 93% amino acid (aa) sequence identity with mouse NFU1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NFU1

Target: NFU1 (NFU1 Iron-Sulfur Cluster Scaffold (NFU1))

Alternative Name: NFU1

Background:

Background: This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: NFU1 iron-sulfur cluster scaffold

Gene ID: 27247

UniProt: Q9UMS0