NFU1 antibody (AA 42-254) (HRP)

Catalog No. ABIN8015335

The HRP-conjugated Rabbit Polyclonal anti-NFU1 antibody (ABIN8015335) specifically detects NFU1 in WB, IHC and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NFU1 antibody (AA 42-254) (HRP) (ABIN8015335)

Target: NFU1 (NFU1 Iron-Sulfur Cluster Scaffold (NFU1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFU1 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-NFU1 Antibody (HRP)

Binding Specificity: AA 42-254

Purpose: Anti-NFU1 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human NFU1 shares 93% amino acid (aa) sequence identity with mouse NFU1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NFU1 recombinant protein (Position: Q42-P254). Human NFU1 shares 93% amino acid (aa) sequence identity with mouse NFU1.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NFU1

Target: NFU1 (NFU1 Iron-Sulfur Cluster Scaffold (NFU1))

Alternative Name: NFU1

Background:

Background: This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: NFU1 iron-sulfur cluster scaffold

Gene ID: 27247

UniProt: Q9UMS0