NFU1 antibody (AA 42-254) (PE)

Catalog No. ABIN8015337

The Rabbit Polyclonal anti-NFU1 antibody is suitable to detect NFU1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IF, FACS and ICC.

Quick Overview for NFU1 antibody (AA 42-254) (PE) (ABIN8015337)

Target: NFU1 (NFU1 Iron-Sulfur Cluster Scaffold (NFU1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFU1 antibody is conjugated to PE

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Product Details anti-NFU1 Antibody (PE)

Binding Specificity: AA 42-254

Purpose: Anti-NFU1 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human NFU1 shares 93% amino acid (aa) sequence identity with mouse NFU1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NFU1 recombinant protein (Position: Q42-P254). Human NFU1 shares 93% amino acid (aa) sequence identity with mouse NFU1.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Comment:

Applications are recommended based on the unconjugated antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NFU1

Target: NFU1 (NFU1 Iron-Sulfur Cluster Scaffold (NFU1))

Alternative Name: NFU1

Background:

Background: This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: NFU1 iron-sulfur cluster scaffold

Gene ID: 27247

UniProt: Q9UMS0