NMNAT1 antibody (AA 56-279) (Biotin)

Catalog No. ABIN8015472

The Rabbit Polyclonal anti-NMNAT1 antibody is suitable to detect NMNAT1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for NMNAT1 antibody (AA 56-279) (Biotin) (ABIN8015472)

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NMNAT1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NMNAT1 Antibody (Biotin)

Binding Specificity: AA 56-279

Purpose: Anti-NMNAT1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human NMNAT1 shares 81.2% amino acid (aa) sequence identity with mouse NMNAT1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NMNAT1 recombinant protein (Position: K56-T279). Human NMNAT1 shares 81.2% amino acid (aa) sequence identity with mouse NMNAT1.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NMNAT1

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Alternative Name: NMNAT1

Background:

Background: This gene encodes an enzyme which catalyzes a key step in the biosynthesis of nicotinamide adenine dinucleotide (NAD). The encoded enzyme is one of several nicotinamide nucleotide adenylyltransferases, and is specifically localized to the cell nucleus. Activity of this protein leads to the activation of a nuclear deacetylase that functions in the protection of damaged neurons. Mutations in this gene have been associated with Leber congenital amaurosis 9. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on chromosomes 1, 3, 4, 14, and 15.

Gene Full Name: nicotinamide nucleotide adenylyltransferase 1

Gene ID: 64802

UniProt: Q9HAN9