NAMPT antibody (AA 62-337) (Fluoro550)

Catalog No. ABIN8015497

The Fluoro550-conjugated Rabbit Polyclonal anti-NAMPT antibody (ABIN8015497) specifically detects NAMPT in FACS. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for NAMPT antibody (AA 62-337) (Fluoro550) (ABIN8015497)

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAMPT antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-NAMPT Antibody (Fluoro550)

Binding Specificity: AA 62-337

Purpose: Anti-Visfatin/NAMPT Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: coli-derived human Visfatin recombinant protein (Position: L62-N337). Human Visfatin shares 97.1%,96.7% amino acid (aa) sequence identity with mouse,rat Visfatin,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Visfatin recombinant protein (Position: L62-N337). Human Visfatin shares 97.1% and 96.7% amino acid (aa) sequence identity with mouse and rat Visfatin, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NAMPT

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Alternative Name: NAMPT

Background:

Background: Nicotinamide phosphoribosyltransferase (NAmPRTase or Nampt), also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin, is an enzyme that in humans is encoded by the PBEF1 gene. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10.

Gene Full Name: nicotinamide phosphoribosyltransferase

Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.

Gene ID: 10135

UniProt: P43490