NFRKB antibody (AA 270-994)

Catalog No. ABIN8016594

The Rabbit Polyclonal anti-NFRKB antibody is suitable to detect NFRKB in samples from Human. It has been validated for WB, ELISA, FACS, IF and ICC.

Quick Overview for NFRKB antibody (AA 270-994) (ABIN8016594)

Target: NFRKB (Nuclear Factor Related To KappaB Binding Protein (NFRKB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFRKB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Grade: Carrier-free

Product Details anti-NFRKB Antibody

Binding Specificity: AA 270-994

Purpose: Anti-NFRKB Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-NFRKB Antibody. Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NFRKB recombinant protein (Position: H270-L994).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NFRKB

Target: NFRKB (Nuclear Factor Related To KappaB Binding Protein (NFRKB))

Alternative Name: NFRKB

Background:

Background: NFRKB (nuclear factor related to kappa-B-binding protein) was first identified as a factor that could bind a variant NF-kappa B site in the interleukin-2 receptor alpha (IL-2R alpha) gene. NFRKB appears to be a transcription factor central to immune cell development. Evidence of this comes from the identification of NFRKB as an amplified gene in several cases of acute myeloid leukemia. Additionally, in another clinical case, a partial deletion of the chromosomal region that includes NFRKB is shown to be associated with combined cellular immunodeficiency.

Gene Full Name: nuclear factor related to kappaB binding protein

Molecular Weight: 175 kDa

Gene ID: 4798

UniProt: Q6P4R8