SIL1 antibody (AA 32-448) (Biotin)

Catalog No. ABIN8017564

The Biotin-conjugated Rabbit Polyclonal anti-SIL1 antibody (ABIN8017564) specifically detects SIL1 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SIL1 antibody (AA 32-448) (Biotin) (ABIN8017564)

Target: SIL1 (Nucleotide Exchange Factor SIL1 (SIL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIL1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SIL1 Antibody (Biotin)

Binding Specificity: AA 32-448

Purpose: Anti-SIL1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human SIL1 shares 86.2% amino acid (aa) sequence identity with both mouse,rat SIL1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SIL1 recombinant protein (Position: H32-E448). Human SIL1 shares 86.2% amino acid (aa) sequence identity with both mouse and rat SIL1.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SIL1

Target: SIL1 (Nucleotide Exchange Factor SIL1 (SIL1))

Alternative Name: SIL1

Background:

Background: This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized.

Gene Full Name: SIL1 nucleotide exchange factor

Gene ID: 64374

UniProt: Q9H173

Pathways: Unfolded Protein Response, SARS-CoV-2 Protein Interactome