SIL1 antibody (AA 32-448) (Fluoro488)

Catalog No. ABIN8017566

The Rabbit Polyclonal anti-SIL1 antibody is suitable to detect SIL1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for SIL1 antibody (AA 32-448) (Fluoro488) (ABIN8017566)

Target: SIL1 (Nucleotide Exchange Factor SIL1 (SIL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIL1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-SIL1 Antibody (Fluoro488)

Binding Specificity: AA 32-448

Purpose: Anti-SIL1 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human SIL1 shares 86.2% amino acid (aa) sequence identity with both mouse,rat SIL1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SIL1 recombinant protein (Position: H32-E448). Human SIL1 shares 86.2% amino acid (aa) sequence identity with both mouse and rat SIL1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SIL1

Target: SIL1 (Nucleotide Exchange Factor SIL1 (SIL1))

Alternative Name: SIL1

Background:

Background: This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized.

Gene Full Name: SIL1 nucleotide exchange factor

Gene ID: 64374

UniProt: Q9H173

Pathways: Unfolded Protein Response, SARS-CoV-2 Protein Interactome