NUF2 antibody (AA 1-297) (FITC)

Catalog No. ABIN8017767

The Rabbit Polyclonal anti-NUF2 antibody is suitable to detect NUF2 in samples from Human. It has been validated for FACS.

Quick Overview for NUF2 antibody (AA 1-297) (FITC) (ABIN8017767)

Target: NUF2 (NUF2, NDC80 Kinetochore Complex Component (NUF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUF2 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-NUF2 Antibody (FITC)

Binding Specificity: AA 1-297

Purpose: Anti-NUF2 Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NUF2 recombinant protein (Position: M1-Q297).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NUF2

Target: NUF2 (NUF2, NDC80 Kinetochore Complex Component (NUF2))

Alternative Name: NUF2

Background:

Background: Kinetochore protein Nuf2 is a protein that in humans is encoded by the NUF2 gene. This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described.

Gene Full Name: NUF2 component of NDC80 kinetochore complex

Gene ID: 83540

UniProt: Q9BZD4

Pathways: Maintenance of Protein Location