Occludin antibody (AA 7-367) (FITC)

Catalog No. ABIN8017888

The FITC-conjugated Rabbit Polyclonal anti-Occludin antibody (ABIN8017888) specifically detects Occludin in FACS. The antibody is reactive with Mouse and Rat samples.

Quick Overview for Occludin antibody (AA 7-367) (FITC) (ABIN8017888)

Target: Occludin (OCLN)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Occludin antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-Occludin Antibody (FITC)

Binding Specificity: AA 7-367

Purpose: Anti-Occludin/Ocln Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Occludin/Ocln recombinant protein (Position: E7-Y367).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Occludin

Target: Occludin (OCLN)

Alternative Name: Ocln

Background:

Background: Occludin is an enzyme (EC 1.6) that oxidizes NADH. Predicted to enable protein domain specific binding activity. Involved in negative regulation of gene expression and tight junction organization. Located in several cellular components, including apical plasma membrane, apicolateral plasma membrane, and bicellular tight junction. Is expressed in several structures, including alimentary system, brain, genitourinary system, respiratory system, and sensory organ. Human ortholog(s) of this gene implicated in Crohn's disease and pseudo-TORCH syndrome 1. Orthologous to human OCLN (occludin).

Gene Full Name: occludin

Gene ID: 18260

UniProt: Q61146

Pathways: Cell-Cell Junction Organization, Hepatitis C