Occludin antibody (AA 7-367)

Catalog No. ABIN8017893

The Rabbit Polyclonal anti-Occludin antibody is suitable to detect Occludin in samples from Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for Occludin antibody (AA 7-367) (ABIN8017893)

Target: Occludin (OCLN)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Occludin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-Occludin Antibody

Binding Specificity: AA 7-367

Purpose: Anti-Occludin/Ocln Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Occludin/Ocln Antibody. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Occludin/Ocln recombinant protein (Position: E7-Y367).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Occludin

Target: Occludin (OCLN)

Alternative Name: Ocln

Background:

Background: Occludin is an enzyme (EC 1.6) that oxidizes NADH. Predicted to enable protein domain specific binding activity. Involved in negative regulation of gene expression and tight junction organization. Located in several cellular components, including apical plasma membrane, apicolateral plasma membrane, and bicellular tight junction. Is expressed in several structures, including alimentary system, brain, genitourinary system, respiratory system, and sensory organ. Human ortholog(s) of this gene implicated in Crohn's disease and pseudo-TORCH syndrome 1. Orthologous to human OCLN (occludin).

Gene Full Name: occludin

Molecular Weight: 59 kDa

Gene ID: 18260

UniProt: Q61146

Pathways: Cell-Cell Junction Organization, Hepatitis C