Mu Opioid Receptor 1 antibody (AA 33-321) (Fluoro550)

Catalog No. ABIN8018183

This Rabbit Polyclonal antibody specifically detects Mu Opioid Receptor 1 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Mu Opioid Receptor 1 antibody (AA 33-321) (Fluoro550) (ABIN8018183)

Target: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mu Opioid Receptor 1 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-Mu Opioid Receptor 1 Antibody (Fluoro550)

Binding Specificity: AA 33-321

Purpose: Anti-OPRM1 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human OPRM1 recombinant protein (Position: N33-H321).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Mu Opioid Receptor 1

Target: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Alternative Name: OPRM1

Background:

Background: This gene encodes one of at least three opioid receptors in humans, the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains.

Gene Full Name: opioid receptor mu 1

Gene ID: 4988

UniProt: P35372

Pathways: cAMP Metabolic Process, Synaptic Membrane