ORC5 antibody (Middle Region) (PE)

Catalog No. ABIN8018399

This Rabbit Polyclonal antibody specifically detects ORC5 in FACS. It exhibits reactivity toward Human, Mouse, Rat and Monkey.

Quick Overview for ORC5 antibody (Middle Region) (PE) (ABIN8018399)

Target: ORC5 (Origin Recognition Complex, Subunit 5 (ORC5))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC5 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-ORC5 Antibody (PE)

Binding Specificity: Middle Region

Purpose: Anti-ORC5L/ORC5 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related mouse sequence.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human ORC5, identical to the related mouse sequence.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ORC5

Target: ORC5 (Origin Recognition Complex, Subunit 5 (ORC5))

Alternative Name: ORC5

Background:

Background: Origin recognition complex subunit 5 is a protein that in humans is encoded by the ORC5 (ORC5L) gene. The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Gene Full Name: origin recognition complex subunit 5

Gene ID: 5001

UniProt: O43913

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA