P-Cadherin antibody (AA 236-645) (HRP)

Catalog No. ABIN8018926

The HRP-conjugated Rabbit Polyclonal anti-P-Cadherin antibody (ABIN8018926) specifically detects P-Cadherin in WB, IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for P-Cadherin antibody (AA 236-645) (HRP) (ABIN8018926)

Target: P-Cadherin (CDH3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P-Cadherin antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-P-Cadherin Antibody (HRP)

Binding Specificity: AA 236-645

Purpose: Anti-P cadherin/CDH3 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human P cadherin/CDH3 recombinant protein (Position: Q236-E645).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for P-Cadherin

Target: P-Cadherin (CDH3)

Alternative Name: CDH3

Background:

Background: Cadherins, such as CDH3, are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion. Cadherin-3 is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.

Gene Full Name: cadherin 3

Gene ID: 1001

UniProt: P22223