PARD6B antibody (AA 89-362) (Fluoro647)

Catalog No. ABIN8019448

The Fluoro647-conjugated Rabbit Polyclonal anti-PARD6B antibody (ABIN8019448) specifically detects PARD6B in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PARD6B antibody (AA 89-362) (Fluoro647) (ABIN8019448)

Target: PARD6B (Par-6 Partitioning Defective 6 Homolog beta (PARD6B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARD6B antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-PARD6B Antibody (Fluoro647)

Binding Specificity: AA 89-362

Purpose: Anti-PARD6B Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human PARD6B shares 89.1% amino acid (aa) sequence identity with mouse PARD6B.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PARD6B recombinant protein (Position: L89-L362). Human PARD6B shares 89.1% amino acid (aa) sequence identity with mouse PARD6B.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PARD6B

Target: PARD6B (Par-6 Partitioning Defective 6 Homolog beta (PARD6B))

Alternative Name: PARD6B

Background:

Background: Partitioning defective 6 homolog beta is a protein that in humans is encoded by the PARD6B gene. This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex.

Gene Full Name: par-6 family cell polarity regulator beta

Gene ID: 84612

UniProt: Q9BYG5

Pathways: Cell-Cell Junction Organization