PALB2 antibody (AA 45-1186) (Fluoro594)

Catalog No. ABIN8019684

The Rabbit Polyclonal anti-PALB2 antibody is suitable to detect PALB2 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for PALB2 antibody (AA 45-1186) (Fluoro594) (ABIN8019684)

Target: PALB2 (Partner and Localizer of BRCA2 (PALB2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PALB2 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-PALB2 Antibody (Fluoro594)

Binding Specificity: AA 45-1186

Purpose: Anti-PALB2 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PALB2 recombinant protein (Position: K45-S1186).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PALB2

Target: PALB2 (Partner and Localizer of BRCA2 (PALB2))

Alternative Name: PALB2

Background:

Background: Partner and localizer of BRCA2, also known as PALB2 or FANCN, is a protein which in humans is encoded by the PALB2 gene. This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2.

Gene Full Name: partner and localizer of BRCA2

Gene ID: 79728

UniProt: Q86YC2

Pathways: DNA Damage Repair