PPAN antibody (AA 20-288) (HRP)

Catalog No. ABIN8020879

The HRP-conjugated Rabbit Polyclonal anti-PPAN antibody (ABIN8020879) specifically detects PPAN in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for PPAN antibody (AA 20-288) (HRP) (ABIN8020879)

Target: PPAN (Peter Pan Homolog (PPAN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPAN antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PPAN Antibody (HRP)

Binding Specificity: AA 20-288

Purpose: Anti-PPAN Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PPAN recombinant protein (Position: R20-E288).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PPAN

Target: PPAN (Peter Pan Homolog (PPAN))

Alternative Name: PPAN

Background:

Background: Suppressor of SWI4 1 homolog is a protein that in humans is encoded by the PPAN gene. The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.

Gene Full Name: peter pan homolog

Gene ID: 56342

UniProt: Q9NQ55