PHF6 antibody (AA 37-309) (Fluoro488)

Catalog No. ABIN8021034

The Rabbit Polyclonal anti-PHF6 antibody is suitable to detect PHF6 in samples from Human, Mouse, Rat and Monkey. It has been validated for FACS.

Quick Overview for PHF6 antibody (AA 37-309) (Fluoro488) (ABIN8021034)

Target: PHF6 (PHD Finger Protein 6 (PHF6))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF6 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-PHF6 Antibody (Fluoro488)

Binding Specificity: AA 37-309

Purpose: Anti-PHF6 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human PHF6 shares 98.2% amino acid (aa) sequence identity with mouse PHF6.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PHF6 recombinant protein (Position: Q37-D309). Human PHF6 shares 98.2% amino acid (aa) sequence identity with mouse PHF6.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PHF6

Target: PHF6 (PHD Finger Protein 6 (PHF6))

Alternative Name: PHF6

Background:

Background: PHD finger protein 6 is a protein that in humans is encoded by the PHF6 gene. This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by cognitive disability, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate splicing results in multiple transcript variants, encoding different isoforms.

Gene Full Name: PHD finger protein 6

Gene ID: 84295

UniProt: Q8IWS0