Phenylalanine Hydroxylase antibody (AA 71-208) (Fluoro550)

Catalog No. ABIN8021068

The Fluoro550-conjugated Rabbit Polyclonal anti-Phenylalanine Hydroxylase antibody (ABIN8021068) specifically detects Phenylalanine Hydroxylase in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Phenylalanine Hydroxylase antibody (AA 71-208) (Fluoro550) (ABIN8021068)

Target: Phenylalanine Hydroxylase

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phenylalanine Hydroxylase antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-Phenylalanine Hydroxylase Antibody (Fluoro550)

Binding Specificity: AA 71-208

Purpose: Anti-PAH Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human PAH recombinant protein (Position: R71-H208). Human PAH shares 89.1%,88.4% amino acid (aa) sequence identity with mouse,rat PAH,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human PAH recombinant protein (Position: R71-H208). Human PAH shares 89.1% and 88.4% amino acid (aa) sequence identity with mouse and rat PAH, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Phenylalanine Hydroxylase

Target: Phenylalanine Hydroxylase

Alternative Name: PAH

Background:

Background: Phenylalanine hydroxylase (PAH) is an enzyme that catalyzes the hydroxylation of the aromatic side-chain of phenylalanine to generate tyrosine. It is one of three members of the biopterin-dependent aromatic amino acid hydroxylases, a class of monooxygenase that uses tetrahydrobiopterin (BH4, a pteridine cofactor) and a non-heme iron for catalysis. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria.

Gene Full Name: phenylalanine hydroxylase

Gene ID: 5053

UniProt: P00439