PDE4C antibody (N-Term) (FITC)

Catalog No. ABIN8021451

The Rabbit Polyclonal anti-PDE4C antibody is suitable to detect PDE4C in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for PDE4C antibody (N-Term) (FITC) (ABIN8021451)

Target: PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE4C antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-PDE4C Antibody (FITC)

Binding Specificity: N-Term

Purpose: Anti-PDE4C Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human PDE4C.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PDE4C

Target: PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))

Alternative Name: PDE4C

Background:

Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: phosphodiesterase 4C

Gene ID: 5143

UniProt: Q08493

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process