PDE6D antibody (N-Term) (PE)

Catalog No. ABIN8021543

This Rabbit Polyclonal antibody specifically detects PDE6D in WB, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PDE6D antibody (N-Term) (PE) (ABIN8021543)

Target: PDE6D (phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE6D antibody is conjugated to PE

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PDE6D Antibody (PE)

Binding Specificity: N-Term

Purpose: Anti-PDE6D Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human PDE6D shares 95.7% amino acid (aa) sequence identity with mouse PDE6D.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human PDE6D. Human PDE6D shares 95.7% amino acid (aa) sequence identity with mouse PDE6D.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human

Comment:

Applications are recommended based on the unconjugated antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PDE6D

Target: PDE6D (phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D))

Alternative Name: PDE6D

Background:

Background: This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.

Gene Full Name: phosphodiesterase 6D

Gene ID: 5147

UniProt: O43924