PDE6D antibody (N-Term)

Catalog No. ABIN8021545

The Rabbit Polyclonal anti-PDE6D antibody (ABIN8021545) specifically detects PDE6D in WB, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PDE6D antibody (N-Term) (ABIN8021545)

Target: PDE6D (phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE6D antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Grade: Carrier-free

Product Details anti-PDE6D Antibody

Binding Specificity: N-Term

Purpose: Anti-PDE6D Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human PDE6D shares 95.7% amino acid (aa) sequence identity with mouse PDE6D.

Characteristics: Anti-PDE6D Antibody. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human PDE6D. Human PDE6D shares 95.7% amino acid (aa) sequence identity with mouse PDE6D.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PDE6D

Target: PDE6D (phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D))

Alternative Name: PDE6D

Background:

Background: This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.

Gene Full Name: phosphodiesterase 6D

Molecular Weight: 15 kDa

Gene ID: 5147

UniProt: O43924