PFKL antibody (Middle Region) (PE)

Catalog No. ABIN8021611

The PE-conjugated Rabbit Polyclonal anti-PFKL antibody (ABIN8021611) specifically detects PFKL in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PFKL antibody (Middle Region) (PE) (ABIN8021611)

Target: PFKL (Phosphofructokinase, Liver (PFKL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFKL antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-PFKL Antibody (PE)

Binding Specificity: Middle Region

Purpose: Anti-PFKL Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human PFKL shares 83.3% amino acid (aa) sequence identity with mouse PFKL.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human PFKL. Human PFKL shares 83.3% amino acid (aa) sequence identity with mouse PFKL.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PFKL

Target: PFKL (Phosphofructokinase, Liver (PFKL))

Alternative Name: PFKL

Background:

Background: This gene encodes the liver (L) subunit of an enzyme that catalyzes the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate, which is a key step in glucose metabolism (glycolysis). This enzyme is a tetramer that may be composed of different subunits encoded by distinct genes in different tissues. Alternative splicing results in multiple transcript variants.

Gene Full Name: phosphofructokinase, liver type

Gene ID: 5211

UniProt: P17858

Pathways: Negative Regulation of Hormone Secretion, Warburg Effect