PGAM2 antibody (N-Term) (Fluoro550)

Catalog No. ABIN8021750

This Rabbit Polyclonal antibody specifically detects PGAM2 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PGAM2 antibody (N-Term) (Fluoro550) (ABIN8021750)

Target: PGAM2 (phosphoglycerate Mutase 2 (Muscle) (PGAM2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGAM2 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-PGAM2 Antibody (Fluoro550)

Binding Specificity: N-Term

Purpose: Anti-PGAM2 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human PGAM2 shares 87% amino acid (aa) sequence identity with both mouse,rat PGAM2.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human PGAM2. Human PGAM2 shares 87% amino acid (aa) sequence identity with both mouse and rat PGAM2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PGAM2

Target: PGAM2 (phosphoglycerate Mutase 2 (Muscle) (PGAM2))

Alternative Name: PGAM2

Background:

Background: Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X.

Gene Full Name: phosphoglycerate mutase 2

Gene ID: 5224

UniProt: P15259