PHPT1 antibody (AA 1-125) (Fluoro488)

Catalog No. ABIN8021782

The Fluoro488-conjugated Rabbit Polyclonal anti-PHPT1 antibody (ABIN8021782) specifically detects PHPT1 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PHPT1 antibody (AA 1-125) (Fluoro488) (ABIN8021782)

Target: PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHPT1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-PHPT1 Antibody (Fluoro488)

Binding Specificity: AA 1-125

Purpose: Anti-PHPT1 Antibody Fluoro488 Conjugated

Predicted Reactivity: Human PHPT1 shares 84.4% amino acid (aa) sequence identity with mouse PHPT1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PHPT1 recombinant protein (Position: M1-Y125). Human PHPT1 shares 84.4% amino acid (aa) sequence identity with mouse PHPT1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PHPT1

Target: PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))

Alternative Name: PHPT1

Background:

Background: 14 kDa phosphohistidine phosphatase is an enzyme that in humans is encoded by the PHPT1 gene. This gene encodes an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. Alternative splicing results in multiple transcript variants.

Gene Full Name: phosphohistidine phosphatase 1

Gene ID: 29085

UniProt: Q9NRX4

Pathways: Positive Regulation of Peptide Hormone Secretion