PIK3R6 antibody (AA 1-537) (APC)

Catalog No. ABIN8021930

This Rabbit Polyclonal antibody specifically detects PIK3R6 in FACS. It exhibits reactivity toward Human.

Quick Overview for PIK3R6 antibody (AA 1-537) (APC) (ABIN8021930)

Target: PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIK3R6 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-PIK3R6 Antibody (APC)

Binding Specificity: AA 1-537

Purpose: Anti-PIK3R6 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PIK3R6 recombinant protein (Position: M1-Q537).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PIK3R6

Target: PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))

Alternative Name: PIK3R6

Background:

Background: Phosphoinositide 3-kinase gamma is a lipid kinase that produces the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. The kinase is composed of a catalytic subunit and one of several regulatory subunits, and is chiefly activated by G protein-coupled receptors. This gene encodes a regulatory subunit, and is distantly related to the phosphoinositide-3-kinase, regulatory subunit 5 gene which is located adjacent to this gene on chromosome 7. The orthologous protein in the mouse binds to both the catalytic subunit and to G(beta/gamma), and mediates activation of the kinase subunit downstream of G protein-coupled receptors. Alternative splicing results in multiple transcript variants.

Gene Full Name: phosphoinositide-3-kinase regulatory subunit 6

Gene ID: 146850

UniProt: Q5UE93

Pathways: PI3K-Akt Signaling, Inositol Metabolic Process