PIF1 antibody (AA 31-618) (Fluoro488)

Catalog No. ABIN8022548

This Rabbit Polyclonal antibody specifically detects PIF1 in FACS. It exhibits reactivity toward Human.

Quick Overview for PIF1 antibody (AA 31-618) (Fluoro488) (ABIN8022548)

Target: PIF1 (PIF1 5'-To-3' DNA Helicase (PIF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIF1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-PIF1 Antibody (Fluoro488)

Binding Specificity: AA 31-618

Purpose: Anti-PIF1 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human PIF1 shares 87.6%,87.8% amino acid (aa) sequence identity with mouse,rat PIF1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PIF1 recombinant protein (Position: Q31-R618). Human PIF1 shares 87.6% and 87.8% amino acid (aa) sequence identity with mouse and rat PIF1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PIF1

Target: PIF1 (PIF1 5'-To-3' DNA Helicase (PIF1))

Alternative Name: PIF1

Background:

Background: This gene encodes a DNA-dependent adenosine triphosphate (ATP)-metabolizing enzyme that functions as a 5' to 3' DNA helicase. The encoded protein can resolve G-quadruplex structures and RNA-DNA hybrids at the ends of chromosomes. It also prevents telomere elongation by inhibiting the actions of telomerase. Alternative splicing and the use of alternative start codons results in multiple isoforms that are differentially localized to either the mitochondria or the nucleus.

Gene Full Name: PIF1 5'-to-3' DNA helicase

Gene ID: 80119

UniProt: Q9H611