PIPOX antibody (AA 173-390) (FITC)

Catalog No. ABIN8022606

The Rabbit Polyclonal anti-PIPOX antibody is suitable to detect PIPOX in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for PIPOX antibody (AA 173-390) (FITC) (ABIN8022606)

Target: PIPOX (Pipecolic Acid Oxidase (PIPOX))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIPOX antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-PIPOX Antibody (FITC)

Binding Specificity: AA 173-390

Purpose: Anti-PIPOX Antibody FITC Conjugated

Predicted Reactivity: Human PIPOX shares 81.2% amino acid (aa) sequence identity with mouse PIPOX.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PIPOX recombinant protein (Position: E173-L390). Human PIPOX shares 81.2% amino acid (aa) sequence identity with mouse PIPOX.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PIPOX

Target: PIPOX (Pipecolic Acid Oxidase (PIPOX))

Alternative Name: PIPOX

Background:

Background: PIPOX (Pipecolic Acid And Sarcosine Oxidase, also known as L-pipecolate oxidase) is a Protein Coding gene. The PIPOX gene, located on 17q11.2, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, C.elegans, S.pombe, N.crassa, A.thaliana, rice, and frog. This enzyme oxidizes L-pipecolic acid with the concomitant production of H2O2 in the peroxisome of the normal human liver. Pipecolate, an intermediate of the lysine catabolic pathway, is oxidized to Δ1 -piperideine-6-carboxylate (P6C) by the PIPOX. Diseases associated with PIPOX include Inflammatory Bowel Disease 15 and Zellweger Syndrome. Among its related pathways are Lysine degradation and Viral mRNA Translation. 215 organisms have orthologs with the human gene PIPOX.

Gene Full Name: pipecolic acid and sarcosine oxidase

Gene ID: 51268

UniProt: Q9P0Z9