PIPOX antibody (AA 173-390)

Catalog No. ABIN8022611

This Rabbit Polyclonal antibody specifically detects PIPOX in ELISA, WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PIPOX antibody (AA 173-390) (ABIN8022611)

Target: PIPOX (Pipecolic Acid Oxidase (PIPOX))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIPOX antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Grade: Carrier-free

Product Details anti-PIPOX Antibody

Binding Specificity: AA 173-390

Purpose: Anti-PIPOX Antibody

Predicted Reactivity: Human PIPOX shares 81.2% amino acid (aa) sequence identity with mouse PIPOX.

Characteristics: Anti-PIPOX Antibody. Tested in WB, IHC, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PIPOX recombinant protein (Position: E173-L390). Human PIPOX shares 81.2% amino acid (aa) sequence identity with mouse PIPOX.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PIPOX

Target: PIPOX (Pipecolic Acid Oxidase (PIPOX))

Alternative Name: PIPOX

Background:

Background: PIPOX (Pipecolic Acid And Sarcosine Oxidase, also known as L-pipecolate oxidase) is a Protein Coding gene. The PIPOX gene, located on 17q11.2, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, C.elegans, S.pombe, N.crassa, A.thaliana, rice, and frog. This enzyme oxidizes L-pipecolic acid with the concomitant production of H2O2 in the peroxisome of the normal human liver. Pipecolate, an intermediate of the lysine catabolic pathway, is oxidized to Δ1 -piperideine-6-carboxylate (P6C) by the PIPOX. Diseases associated with PIPOX include Inflammatory Bowel Disease 15 and Zellweger Syndrome. Among its related pathways are Lysine degradation and Viral mRNA Translation. 215 organisms have orthologs with the human gene PIPOX.

Gene Full Name: pipecolic acid and sarcosine oxidase

Molecular Weight: 40 kDa

Gene ID: 51268

UniProt: Q9P0Z9