PIWIL4 antibody (AA 51-749) (Fluoro594)

Catalog No. ABIN8022683

This Rabbit Polyclonal antibody specifically detects PIWIL4 in FACS. It exhibits reactivity toward Human.

Quick Overview for PIWIL4 antibody (AA 51-749) (Fluoro594) (ABIN8022683)

Target: PIWIL4 (Piwi-Like 4 (PIWIL4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIWIL4 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-PIWIL4 Antibody (Fluoro594)

Binding Specificity: AA 51-749

Purpose: Anti-PIWIL4/PIWI Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PIWIL4/PIWI recombinant protein (Position: R51-N749).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PIWIL4

Target: PIWIL4 (Piwi-Like 4 (PIWIL4))

Alternative Name: PIWIL4

Background:

Background: PIWI-like protein 4 (PIWIL4) is a 97 kDa member of the argonaute family of proteins and the PIWI subfamily. Human PIWIL4 is 852 amino acids (aa) in length and contains one PAZ domain (aa 268-384) and one PIWI domain (aa 546-838). There are three isoforms for human PIWIL4. Isoform 1 is the standard protein. Isoform 2 has a two aa substitution for aa 1-29 in isoform 1 and a deletion of aa 523-852. Isoform 3 has a deletion of aa 1-69 and a deletion of aa 523-852. Human PIWIL4 shares 77 % aa sequence identity with mouse and rat PIWIL4. PIWIL4 plays a central role in spermatogenesis.

Gene Full Name: piwi like RNA-mediated gene silencing 4

Gene ID: 143689

UniProt: Q7Z3Z4