PDGFA antibody (AA 87-211) (Fluoro647)

Catalog No. ABIN8023009

The Fluoro647-conjugated Rabbit Polyclonal anti-PDGFA antibody (ABIN8023009) specifically detects PDGFA in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PDGFA antibody (AA 87-211) (Fluoro647) (ABIN8023009)

Target: PDGFA (Platelet Derived Growth Factor A (PDGFA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFA antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-PDGFA Antibody (Fluoro647)

Binding Specificity: AA 87-211

Purpose: Anti-PDGF AA/PDGFA Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PDGF AA/PDGFA recombinant protein (Position: S87-T211).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PDGFA

Target: PDGFA (Platelet Derived Growth Factor A (PDGFA))

Alternative Name: PDGFA

Background:

Background: Platelet-derived growth factor subunit A is a protein that in humans is encoded by the PDGFA gene. This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants.

Gene Full Name: platelet derived growth factor subunit A

Gene ID: 5154

UniProt: P04085

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling