PRAM1 antibody (AA 361-670) (Fluoro488)

Catalog No. ABIN8023504

The Fluoro488-conjugated Rabbit Polyclonal anti-PRAM1 antibody (ABIN8023504) specifically detects PRAM1 in FACS. The antibody is reactive with Human samples.

Quick Overview for PRAM1 antibody (AA 361-670) (Fluoro488) (ABIN8023504)

Target: PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRAM1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-PRAM1 Antibody (Fluoro488)

Binding Specificity: AA 361-670

Purpose: Anti-PRAM1 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PRAM1 recombinant protein (Position: E361-R670).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PRAM1

Target: PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))

Alternative Name: PRAM1

Background:

Background: PML-RARA-regulated adapter molecule 1 is a protein that in humans is encoded by the PRAM1 gene. The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha).

Gene Full Name: PML-RARA regulated adaptor molecule 1

Gene ID: 84106

UniProt: Q96QH2

Pathways: Regulation of Leukocyte Mediated Immunity