PARP9 antibody (AA 117-824) (Biotin)

Catalog No. ABIN8023876

The Biotin-conjugated Rabbit Polyclonal anti-PARP9 antibody (ABIN8023876) specifically detects PARP9 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PARP9 antibody (AA 117-824) (Biotin) (ABIN8023876)

Target: PARP9 (Poly (ADP-Ribose) Polymerase Family, Member 9 (PARP9))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARP9 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PARP9 Antibody (Biotin)

Binding Specificity: AA 117-824

Purpose: Anti-PARP9 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PARP9 recombinant protein (Position: R117-E824).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PARP9

Target: PARP9 (Poly (ADP-Ribose) Polymerase Family, Member 9 (PARP9))

Alternative Name: PARP9

Background:

Background: Poly (ADP-ribosyl)ation is a post-translational modification of proteins mediated by one of the 17 members of the poly (ADP-ribose) polymerases (PARP). PARP-9 belongs to the subfamily of macroPARPs, associating one to three macro domains to the PARP domain. Overexpression of PARP-9 stimulates cell migration in vitro, suggesting a role for PARP-9 in the promotion of malignant B cell migration and dissemination in high risk DLBCL. PARP-9 is also likely a transcription coactivator, its overexpression in B lymphocytes, stimulated by IFNγ, inducing the transcription of IFNγ-controlled genes.

Gene Full Name: poly(ADP-ribose) polymerase family member 9

Gene ID: 83666

UniProt: Q8IXQ6