PHC1 antibody (AA 23-642) (Biotin)

Catalog No. ABIN8024054

This Rabbit Polyclonal antibody specifically detects PHC1 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for PHC1 antibody (AA 23-642) (Biotin) (ABIN8024054)

Target: PHC1 (Polyhomeotic-Like 1 (PHC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHC1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PHC1 Antibody (Biotin)

Binding Specificity: AA 23-642

Purpose: Anti-PHC1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human PHC1 shares 93.6% amino acid (aa) sequence identity with mouse PHC1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PHC1 recombinant protein (Position: R23-K642). Human PHC1 shares 93.6% amino acid (aa) sequence identity with mouse PHC1.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PHC1

Target: PHC1 (Polyhomeotic-Like 1 (PHC1))

Alternative Name: PHC1

Background:

Background: Polyhomeotic-like protein 1 is a protein that in humans is encoded by the PHC1 gene. This gene is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. The gene product, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein.

Gene Full Name: polyhomeotic homolog 1

Gene ID: 1911

UniProt: P78364