POLR1D antibody (AA 10-133) (FITC)

Catalog No. ABIN8024247

The Rabbit Polyclonal anti-POLR1D antibody is suitable to detect POLR1D in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for POLR1D antibody (AA 10-133) (FITC) (ABIN8024247)

Target: POLR1D (Polymerase (RNA) I Polypeptide D, 16kDa (POLR1D))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR1D antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-POLR1D Antibody (FITC)

Binding Specificity: AA 10-133

Purpose: Anti-POLR1D Antibody FITC Conjugated

Predicted Reactivity: Human POLR1D shares 90.3% amino acid (aa) sequence identity with mouse POLR1D.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human POLR1D recombinant protein (Position: K10-F133). Human POLR1D shares 90.3% amino acid (aa) sequence identity with mouse POLR1D.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for POLR1D

Target: POLR1D (Polymerase (RNA) I Polypeptide D, 16kDa (POLR1D))

Alternative Name: POLR1D

Background:

Background: DNA-ed RNA polymerases I and III subunit RPAC2 is a protein that in humans is encoded by the POLR1D gene. The protein encoded by this gene is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in this gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder. Alternative splicing results in multiple transcript variants.

Gene Full Name: RNA polymerase I and III subunit D

Gene ID: 51082

UniProt: P0DPB6